Physics NEET Full Syllabus Mock Test 180 Question New Syllabus Mock Test - 15 PCB MCQ (Single Correct)

Which pair of functional groups from adjacent nucleotides reacts to form the phosphodiester bond in a polynucleotide chain?

A
The 3'-OH of one sugar and the 5' -phosphate of the next sugar
B
The 2'- OH of one sugar and the 5'-phosphate of the next sugar
C
The 3'-phosphate of one sugar and the 5'-OH of the next sugar
D
The N -atom of the base of one nucleotide and the 5'-phosphate of the next

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The correct answer is:
A

Nucleotides polymerize via a phosphodiester linkage: the of one pentose condenses with the phosphate on the -carbon of the next nucleotide.

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